BMI206: Statistical Methods
OVERVIEW – SYLLABUS – READING – LABS – TUTORIALS – PROJECT
Reading List
These papers provide examples of the topics in the course from the recent literature. They will be discussed in class on Wednesdays unless otherwise indicated. Papers marked (*) will form the basis of the final project.
| Date | Paper | PMID | Questions |
|---|---|---|---|
| Pre-requisite | Empowering statistical methods for cellular and molecular biologists | PMID: 31145670 | Discussion questions |
| Oct 16 | * Improving polygenic prediction in ancestrally diverse populations | PMID: 35513724 | Discussion questions |
| Oct 23 | pyPAGE: A framework for Addressing biases in gene-set enrichment analysis-A case study on Alzheimer’s disease | PMID: 39236079 | Discussion questions |
| Oct 30 | Navigating the pitfalls of applying machine learning in genomics | PMID: 34837041 | Discussion questions |
| Nov 14 | * Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles | PMID: 38594305 | Discussion questions |
| Nov 20 | * Identification of critical connectors in the directed reaction-centric graphs of microbial metabolic networks | PMID: 31195955 | Discussion questions |
| Dec 4 | The art of using t-SNE The specious art of single-cell genomics |
PMID: 31780648 | Discussion questions |