Human Acceleration in Primate Conserved Elements

31-species multiz alignments,
phastCons elements using only primates with hg18 excluded,
filtered for

macaque, dog and mouse synteny (level 1 or 2, non-gap),
no pseudogenes,
no segmental duplications,
no repeats,
no selfChain

-> 920,486 elements,

phyloP likelihood ratio tests (LRT), score=-log p-value truncated at 20,
Benjamini-Hochberg false discovery rate (FDR) adjustment

1,930 elements with FDR less than 0.1: Download the BED file (other details shown below)

Location(hg18) Length (bp) LRT score FDR adjusted p-value
chrX:137621116-137621212 97 20 3.068e-15
chr20:61203910-61204071 162 20 3.068e-15
chr2:236438431-236438915 485 20 3.068e-15
chr13:72012994-72013419 426 12.878 3.048e-08
chr20:656951-657069 119 12.029 1.722e-07
chrX:137548644-137548665 22 11.435 5.571e-07
chr9:1035539-1035645 107 11.333 5.571e-07
chr3:6882035-6882107 73 11.315 5.571e-07
chr2:238397678-238397785 108 10.91 1.258e-06
chr7:2172450-2172640 191 10.821 1.39e-06
chr20:35912963-35913128 166 10.44 3.038e-06
chr15:96056873-96057063 191 10.101 5.958e-06
chr2:113709421-113709711 291 10.075 5.958e-06
chr20:15345679-15345761 83 9.83 9.725e-06
chr2:192947134-192947158 25 9.648 1.38e-05
chr18:55171406-55171515 110 9.544 1.605e-05
chr9:3959050-3959173 124 9.528 1.605e-05
chr2:177391443-177391464 22 9.208 3.168e-05
chr4:182819703-182819953 251 9.031 4.511e-05
chr4:182508876-182509941 1066 8.684 9.528e-05
chr14:75857010-75857092 83 8.606 0.0001086
chr2:118783627-118784214 588 8.525 0.0001249
chr17:2150122-2150236 115 8.448 0.0001427
chr3:74212961-74213146 186 8.391 0.0001503
chr2:114205619-114205699 81 8.389 0.0001503
chr8:4007074-4007118 45 8.194 0.0002265
chr3:149086056-149086627 572 8.07 0.0002902
chr12:869870-869946 77 8.045 0.0002964
chr15:34178772-34179093 322 7.988 0.0003263
chr14:32141053-32141065 13 7.953 0.0003419
chr16:77759971-77759993 23 7.938 0.0003425
chr16:78637352-78637617 266 7.898 0.0003638
chr10:9281951-9282604 654 7.784 0.0004587
chr18:57447702-57447938 237 7.752 0.0004792
chr11:117127006-117127472 467 7.731 0.0004886
chr13:99924151-99924344 194 7.666 0.0005517
chr14:29673875-29674445 571 7.63 0.0005794
chr12:844522-844805 284 7.619 0.0005794
chr8:38357328-38357359 32 7.61 0.0005794
chr6:1232688-1232869 182 7.55 0.0006401
chr15:94993162-94993420 259 7.545 0.0006401
chr9:13745709-13746164 456 7.531 0.0006453
chr10:108799416-108799548 133 7.418 0.0008176
chr6:50309839-50310231 393 7.329 0.0009808
chr9:697069-697097 29 7.303 0.001006
chr7:134030644-134030806 163 7.29 0.001006
chr13:70621815-70622200 386 7.287 0.001006
chr18:3205052-3205227 176 7.28 0.001006
chr3:2392388-2392559 172 7.215 0.001145
chr7:10116283-10116858 576 7.2 0.001162
chr1:241569035-241569089 55 7.169 0.001208
chr13:76477846-76477889 44 7.166 0.001208
chr4:30262356-30262505 150 7.104 0.001367
chr2:146903602-146903618 17 7.039 0.001558
chr2:169550864-169551103 240 6.959 0.001808
chr16:77757132-77757445 314 6.956 0.001808
chr16:77396095-77396306 212 6.951 0.001808
chr6:2341483-2341595 113 6.928 0.001841
chr14:27669360-27670038 679 6.928 0.001841
chr3:71054297-71054374 78 6.882 0.001994
chr1:53566135-53566172 38 6.879 0.001994
chr3:4749770-4749907 138 6.868 0.002012
chr2:220436447-220436496 50 6.844 0.002093
chr2:145585163-145585300 138 6.83 0.002127
chr11:8340320-8340776 457 6.814 0.002173
chr13:67092852-67093078 227 6.781 0.002309
chr20:604375-604581 207 6.754 0.002421
chr13:38255193-38255261 69 6.707 0.002658
chr2:142294064-142294150 87 6.688 0.002722
chr20:7834156-7834178 23 6.684 0.002722
chr21:17137554-17137656 103 6.664 0.00281
chr7:16010795-16011298 504 6.658 0.00281
chr18:898800-898990 191 6.643 0.002818
chr9:14779373-14779438 66 6.639 0.002818
chr4:182818418-182818974 557 6.639 0.002818
chr16:49659136-49659217 82 6.631 0.002833
chr4:96789861-96789873 13 6.616 0.002894
chr15:92714022-92714107 86 6.57 0.003126
chr5:168931098-168931206 109 6.568 0.003126
chr16:77549488-77549969 482 6.566 0.003126
chrX:131919852-131919895 44 6.524 0.003382
chr22:47883343-47883541 199 6.521 0.003382
chr16:7299813-7299983 171 6.504 0.003475
chr16:77075028-77075201 174 6.497 0.003489
chr7:25324190-25324628 439 6.482 0.003528
chr8:99536885-99536968 84 6.478 0.003528
chr14:94730392-94730476 85 6.477 0.003528
chr18:898224-898371 148 6.465 0.003585
chr10:8616160-8616591 432 6.458 0.003603
chrX:138116229-138116552 324 6.44 0.003713
chr9:262925-263030 106 6.432 0.003741
chr14:36678006-36678357 352 6.421 0.003795
chr1:36588182-36588278 97 6.409 0.00386
chr4:28589094-28589121 28 6.403 0.003872
chr12:12627324-12627421 98 6.377 0.004067
chr9:9338335-9338508 174 6.356 0.004219
chr8:5390677-5390703 27 6.352 0.004219
chr6:57506079-57506287 209 6.34 0.004289
chr9:16708053-16708274 222 6.336 0.004289
chr9:2040741-2041009 269 6.324 0.004322
chr7:115156551-115156735 185 6.324 0.004322
chr7:18000933-18000990 58 6.309 0.00443
chr14:27668589-27668852 264 6.294 0.004463
chr7:88960332-88960524 193 6.291 0.004463
chr7:9029695-9029734 40 6.291 0.004463
chr20:6579939-6580047 109 6.287 0.004463
chr6:98893963-98894010 48 6.285 0.004463
chr2:182408124-182408241 118 6.269 0.004588
chr7:15728693-15728730 38 6.256 0.004684
chr1:82244592-82244643 52 6.243 0.004782
chr15:94529372-94529571 200 6.231 0.004839
chr2:21328791-21329288 498 6.23 0.004839
chr1:82993506-82993837 332 6.226 0.004841
chr9:27589198-27589296 99 6.208 0.005002
chr17:2149681-2149848 168 6.177 0.005291
chr13:76994189-76994312 124 6.176 0.005291
chr7:154441036-154441158 123 6.169 0.005302
chr11:126518818-126518870 53 6.166 0.005302
chr14:46379164-46379488 325 6.164 0.005302
chr2:80041114-80041319 206 6.153 0.005393
chr4:16422825-16423001 177 6.137 0.005549
chr20:8581373-8581464 92 6.133 0.005555
chr8:144632724-144633109 386 6.125 0.005612
chr21:21287639-21287735 97 6.115 0.005696
chr9:28022040-28022064 25 6.089 0.005979
chr14:48415946-48415967 22 6.087 0.005979
chr16:76916604-76917105 502 6.079 0.006042
chr13:59837524-59837553 30 6.072 0.006093
chr4:23484741-23485071 331 6.059 0.006229
chr9:16698802-16699094 293 6.053 0.006267
chr8:116489660-116489673 14 6.044 0.00635
chr1:19560723-19560995 273 6.039 0.006356
chr7:13999177-13999189 13 6.037 0.006356
chr5:166626996-166627391 396 6.033 0.00636
chr2:29563481-29563572 92 6.029 0.00636
chrX:130970555-130970635 81 6.027 0.00636
chr16:6699306-6699783 478 5.997 0.006696
chr16:7385626-7385838 213 5.993 0.006696
chr7:19583620-19583717 98 5.992 0.006696
chr12:71568943-71568955 13 5.992 0.006696
chr7:115309721-115309767 47 5.989 0.006696
chr22:45619976-45620036 61 5.979 0.006803
chr14:78112048-78112321 274 5.959 0.007074
chr18:3184530-3184614 85 5.955 0.00709
chr18:35405612-35405690 79 5.95 0.007123
chr3:140976324-140976526 203 5.941 0.00719
chr11:20776339-20776615 277 5.938 0.00719
chr10:225031-225063 33 5.937 0.00719
chr3:194902613-194902684 72 5.928 0.007292
chr2:31151968-31152023 56 5.922 0.007344
chr16:72261347-72261506 160 5.909 0.007517
chr9:3947228-3947305 78 5.906 0.007519
chr2:142264213-142264266 54 5.903 0.007522
chr10:114889607-114889965 359 5.899 0.007528
chr4:26817632-26817941 310 5.897 0.007528
chr13:24934189-24934256 68 5.892 0.007562
chr3:75260947-75261118 172 5.888 0.007562
chr6:149229531-149229681 151 5.884 0.007562
chr4:17028409-17028448 40 5.884 0.007562
chr17:2088472-2088724 253 5.874 0.007689
chr8:5473311-5473511 201 5.855 0.007983
chr2:144874349-144874795 447 5.852 0.007989
chr18:36689667-36689812 146 5.84 0.008163
chr20:51053667-51053802 136 5.817 0.008541
chr14:38442492-38442580 89 5.815 0.008541
chr6:142353342-142353368 27 5.807 0.008648
chr2:176141691-176141858 168 5.803 0.008672
chr11:115153416-115153850 435 5.799 0.008672
chr16:80852711-80852840 130 5.798 0.008672
chr3:187439802-187440065 264 5.793 0.008721
chr6:2056510-2056836 327 5.789 0.00875
chr2:177452686-177452931 246 5.785 0.008769
chr5:51834702-51835044 343 5.783 0.008769
chr10:11117737-11117885 149 5.776 0.008861
chr9:23786228-23786560 333 5.772 0.008892
chr4:11480076-11480201 126 5.767 0.008943
chr12:4039849-4039891 43 5.759 0.009049
chr2:163875189-163875247 59 5.757 0.009049
chr3:67770210-67770230 21 5.747 0.009208
chr2:119705597-119705651 55 5.724 0.009655
chr8:83045088-83045248 161 5.718 0.009735
chr12:16062304-16062946 643 5.704 0.009999
chr4:66100978-66101020 43 5.695 0.01015
chr8:100001898-100001959 62 5.691 0.01019
chr7:15264008-15264090 83 5.67 0.01064
chr12:102208173-102208458 286 5.659 0.01085
chr11:130470619-130470890 272 5.656 0.01087
chr4:178510142-178510343 202 5.652 0.01087
chr7:15222017-15222117 101 5.65 0.01087
chr7:4024355-4024605 251 5.649 0.01087
chr3:188772845-188772881 37 5.646 0.01089
chr5:165360893-165360914 22 5.643 0.01091
chr7:1243639-1243673 35 5.638 0.01098
chr9:28110013-28110496 484 5.635 0.011
chr5:165538342-165538481 140 5.628 0.01112
chr14:33118401-33118579 179 5.623 0.01119
chr11:132315139-132315283 145 5.62 0.01121
chr5:24281883-24281940 58 5.602 0.01159
chr11:115420802-115421167 366 5.601 0.01159
chr7:8708748-8708852 105 5.596 0.01167
chr16:60107555-60107734 180 5.589 0.01176
chr10:130734184-130734470 287 5.587 0.01176
chr10:16745455-16745519 65 5.586 0.01176
chr6:106643194-106643258 65 5.576 0.01192
chr13:105743521-105743754 234 5.576 0.01192
chr3:61579302-61579318 17 5.556 0.01223
chr11:11130344-11130407 64 5.556 0.01223
chr1:184061373-184061598 226 5.554 0.01223
chr1:3079671-3079752 82 5.551 0.01223
chr2:223405319-223405334 16 5.546 0.01223
chr12:2234886-2234950 65 5.545 0.01223
chr3:3046938-3046998 61 5.544 0.01223
chr18:70742857-70743070 214 5.544 0.01223
chr11:131379881-131379920 40 5.544 0.01223
chr1:243631247-243631464 218 5.542 0.01223
chr1:241706021-241706318 298 5.542 0.01223
chr16:5448199-5448213 15 5.54 0.01223
chr8:60085978-60086017 40 5.528 0.01252
chr10:107090436-107090668 233 5.526 0.01252
chr4:94794385-94794744 360 5.521 0.01261
chr1:38460494-38460843 350 5.503 0.01308
chr10:33715009-33715132 124 5.496 0.01323
chr5:178765038-178765111 74 5.491 0.01327
chr14:25434883-25434963 81 5.49 0.01327
chr12:3471012-3471027 16 5.489 0.01327
chr5:50783210-50783260 51 5.482 0.01342
chr6:50136771-50137191 421 5.471 0.01371
chr16:6863382-6863544 163 5.468 0.01374
chr6:106158815-106158942 128 5.46 0.01388
chr3:64500454-64500572 119 5.457 0.01388
chr8:40504279-40504383 105 5.456 0.01388
chr2:198935509-198936154 646 5.456 0.01388
chr3:29974813-29974848 36 5.452 0.01389
chr18:34939357-34939378 22 5.452 0.01389
chr11:120146132-120146320 189 5.445 0.01406
chr3:165240996-165241020 25 5.439 0.01415
chr8:6076192-6076266 75 5.437 0.01415
chr3:59348324-59348354 31 5.435 0.01415
chr17:2149855-2150082 228 5.435 0.01415
chr21:34388919-34388935 17 5.429 0.01415
chr13:101171272-101171346 75 5.429 0.01415
chr14:33200072-33200922 851 5.426 0.01415
chr10:17600615-17600779 165 5.426 0.01415
chr14:33229846-33230152 307 5.425 0.01415
chr1:206674809-206674871 63 5.424 0.01415
chr4:43978499-43978530 32 5.422 0.01416
chr14:25416101-25416136 36 5.42 0.01417
chr8:135490667-135490865 199 5.416 0.01424
chr12:112483426-112483659 234 5.409 0.01439
chr4:146728632-146728673 42 5.408 0.01439
chr8:13640209-13640266 58 5.399 0.01461
chr6:91854478-91854557 80 5.398 0.01461
chr22:47740894-47741236 343 5.38 0.01517
chr9:2611397-2611539 143 5.378 0.01518
chr3:149274287-149274585 299 5.374 0.01526
chr6:151430848-151430957 110 5.37 0.01534
chr16:70789611-70789843 233 5.355 0.01582
chr16:7412520-7412733 214 5.346 0.01608
chr16:81252436-81252518 83 5.342 0.01617
chr10:125263669-125263843 175 5.337 0.01629
chr12:56812497-56812587 91 5.332 0.0164
chr16:76161028-76161130 103 5.331 0.0164
chr9:1191847-1191976 130 5.318 0.01681
chr16:75519676-75519920 245 5.315 0.01681
chr20:59637979-59638064 86 5.312 0.01681
chr6:655715-655853 139 5.311 0.01681
chr3:172302540-172302571 32 5.311 0.01681
chr10:225172-225195 24 5.309 0.01681
chr6:99053259-99053510 252 5.306 0.01681
chr21:26548383-26548461 79 5.305 0.01681
chr6:8730079-8730772 694 5.304 0.01681
chr4:98338104-98338249 146 5.304 0.01681
chr2:66767433-66767559 127 5.289 0.01733
chr18:20911913-20912371 459 5.285 0.01743
chr8:4926410-4926534 125 5.28 0.01757
chr5:163650180-163650329 150 5.272 0.01776
chr5:3831280-3831378 99 5.271 0.01776
chr8:66101612-66101857 246 5.27 0.01776
chr13:70795442-70795774 333 5.269 0.01776
chr3:59205462-59205518 57 5.261 0.01802
chr9:1733149-1734026 878 5.259 0.01804
chr2:22035305-22035434 130 5.254 0.01816
chr15:58143647-58144075 429 5.253 0.01816
chr13:105634138-105634407 270 5.25 0.01823
chr5:168245758-168246021 264 5.242 0.0185
chr15:58423812-58424128 317 5.239 0.01856
chr2:20214203-20214249 47 5.237 0.01858
chrX:136339658-136339736 79 5.229 0.01886
chr14:29758282-29758354 73 5.218 0.01928
chr7:27117898-27118112 215 5.216 0.0193
chr18:44754917-44754978 62 5.213 0.01937
chr1:88388371-88389183 813 5.207 0.01951
chr3:176112358-176112534 177 5.206 0.01951
chr2:195403397-195403844 448 5.205 0.01951
chr16:57472657-57472754 98 5.202 0.01951
chr17:52852655-52852717 63 5.201 0.01951
chr11:133526771-133526786 16 5.201 0.01951
chr16:77095180-77095439 260 5.199 0.01951
chr6:23771691-23771795 105 5.198 0.01951
chr9:8274892-8275077 186 5.194 0.01963
chr11:132648028-132648174 147 5.191 0.01968
chr11:98029561-98029730 170 5.19 0.01968
chr2:22978599-22978739 141 5.186 0.0198
chr17:70744336-70744390 55 5.184 0.0198
chr11:114826330-114826658 329 5.183 0.0198
chr1:37844208-37844251 44 5.178 0.01993
chr4:183595280-183595318 39 5.176 0.01993
chr2:116190880-116190937 58 5.176 0.01993
chr2:192432061-192432236 176 5.174 0.01994
chr21:37208766-37208845 80 5.173 0.01994
chr4:22624864-22624886 23 5.167 0.02008
chr15:56337235-56337309 75 5.167 0.02008
chr4:81339244-81339279 36 5.163 0.02021
chr8:94389183-94389527 345 5.161 0.02023
chr14:62825197-62825235 39 5.159 0.02025
chr2:154967281-154967350 70 5.158 0.02025
chr14:36573766-36574086 321 5.155 0.02032
chr11:113605032-113605424 393 5.152 0.02035
chr5:164192286-164192813 528 5.15 0.02035
chr2:172988073-172988091 19 5.149 0.02035
chr11:122537169-122537234 66 5.149 0.02035
chr10:8586796-8587033 238 5.146 0.02041
chr3:69054536-69054577 42 5.145 0.02041
chr18:23864013-23864034 22 5.136 0.02077
chr12:93453154-93453226 73 5.13 0.02096
chr20:1304256-1304278 23 5.129 0.02096
chr3:176682849-176682898 50 5.128 0.02096
chr17:61825494-61825513 20 5.125 0.02098
chr15:34987693-34987806 114 5.125 0.02098
chr13:89163791-89163952 162 5.12 0.02116
chr5:154986230-154986628 399 5.115 0.02128
chr2:41875544-41875627 84 5.115 0.02128
chr1:77304079-77304412 334 5.112 0.02131
chr9:1649862-1650186 325 5.11 0.02131
chr18:23706557-23706787 231 5.11 0.02131
chr2:115414623-115414929 307 5.109 0.02131
chr9:3276536-3276578 43 5.101 0.02165
chr3:135962839-135962865 27 5.097 0.02178
chr11:31787341-31787367 27 5.083 0.02243
chr2:197450457-197450611 155 5.079 0.02257
chr4:78282593-78282691 99 5.077 0.02259
chr1:66774523-66774541 19 5.076 0.02259
chr6:2018266-2018343 78 5.072 0.02274
chr9:2071662-2071822 161 5.068 0.02288
chr1:116141431-116141459 29 5.061 0.02317
chr12:127380307-127380364 58 5.06 0.02317
chr3:193794524-193794635 112 5.056 0.0233
chr5:27470956-27470974 19 5.055 0.0233
chr16:82291998-82292069 72 5.05 0.02336
chr12:28635077-28635101 25 5.05 0.02336
chr5:162947912-162948044 133 5.049 0.02336
chr11:91527630-91527688 59 5.049 0.02336
chr12:42458432-42458460 29 5.045 0.02351
chr22:25540675-25540752 78 5.042 0.02354
chr14:87430560-87430742 183 5.042 0.02354
chr2:67087973-67088026 54 5.036 0.0238
chr2:144554729-144554785 57 5.03 0.02393
chr14:96650213-96650306 94 5.03 0.02393
chr11:31993805-31993909 105 5.03 0.02393
chr13:71633933-71634238 306 5.027 0.02402
chr15:45957184-45957226 43 5.026 0.02402
chr14:43764831-43764862 32 5.021 0.02418
chr2:174144372-174144484 113 5.018 0.02418
chr15:57452145-57452190 46 5.018 0.02418
chr2:229846414-229846577 164 5.017 0.02418
chr18:34010075-34010176 102 5.017 0.02418
chr17:67391482-67391498 17 5.003 0.02491
chr18:23455629-23455814 186 4.997 0.02518
chr16:81676-81732 57 4.996 0.02518
chr7:8196648-8196750 103 4.993 0.02521
chr12:13309953-13310357 405 4.993 0.02521
chr12:18365016-18365238 223 4.99 0.02531
chr11:131286770-131286820 51 4.989 0.02531
chr20:14848735-14848803 69 4.987 0.02535
chr12:23333081-23333094 14 4.986 0.02535
chr7:116713828-116713971 144 4.981 0.0255
chrX:128914604-128914648 45 4.98 0.0255
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chr12:11866704-11866856 153 3.687 0.09913
chr18:71462832-71462907 76 3.686 0.0992
chr15:90426522-90426576 55 3.686 0.0992
chr1:247072735-247073073 339 3.686 0.0992
chrX:144729467-144729550 84 3.685 0.09928
chr4:147987511-147987752 242 3.685 0.09928
chr3:29886256-29886307 52 3.685 0.09928
chr3:41211432-41212040 609 3.684 0.09935
chr13:38131187-38131208 22 3.684 0.09935
chr1:198772990-198773363 374 3.684 0.09935
chr7:20734397-20734417 21 3.683 0.09948
chr1:73995145-73995166 22 3.683 0.09948
chr20:51196391-51196698 308 3.682 0.09965
chr6:91468635-91468739 105 3.681 0.09968
chr4:148652069-148652088 20 3.681 0.09968
chr3:194499053-194499170 118 3.681 0.09968
chr14:81591991-81592190 200 3.681 0.09968
chr8:6392913-6392996 84 3.68 0.09975
chr3:61130191-61130217 27 3.68 0.09975
chr2:230207598-230207641 44 3.68 0.09975
chr11:42429150-42429452 303 3.679 0.09988
chr10:117414462-117414523 62 3.679 0.09988