BMI206: Statistical Methods

OVERVIEWSYLLABUSREADING –  LABS – TUTORIALSPROJECT

Reading List

These papers provide examples of the topics in the course from the recent literature. They will be discussed in class on Wednesdays. Papers marked (*) will form the basis of the final project.

Date Paper PMID Questions
Pre-requisite Empowering statistical methods for cellular and molecular biologists PMID: 31145670 Discussion questions
Oct 12 * Improving polygenic prediction in ancestrally diverse populations PMID: 35513724 Discussion questions
Oct 19 * Gene set enrichment analysis for genome-wide DNA methylation data PMID: 34103055 Discussion questions
Notebook
Oct 26 Navigating the pitfalls of applying machine learning in genomics PMID: 34837041 Discussion questions
Nov 2 * Global reference mapping of human transcription factor footprints PMID: 32728250 Discussion questions
Nov 16 * Identification of critical connectors in the directed reaction-centric graphs of microbial metabolic networks PMID: 31195955 Discussion questions
Nov 30 The art of using t-SNE
The specious art of single-cell genomics
PMID: 31780648 Discussion questions