We are a bioinformatics research lab focused on developing novel methods and using them to study genome evolution, organization, and regulation. Our mission is to decode biomedical knowledge that is missed without rigorous statistical approaches.

Latest News

OCTOBER 2025

We predicted a gene on chromosome 21 contributing to cardiac disease in individuals with Down Syndrome, and the Srivastava lab validated it. Read the story!

SEPTEMBER 2025

Katie and colleagues discuss how our understanding of human-chimp DNA differences is evolving with the increasing number of complete genome sequences for both species. Read the story!

AUGUST 2025

Before heading off to her new faculty position at Oregon State, Zhirui Hu used her CellWalker modeling approach to dissect regulatory pathways in brain vascular cells in collaboration with Andrew Yang’s group. Read the story!

MAY 2025

Our CellWalker2 manuscript appeared today in Cell Genomics! Read the story.

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